The DuraGraft® Difference: Treatment for the Prevention of Vein Graft Disease
Intraoperative Graft Damage is the Principal Cause of Vein Graft Failure.
The durability and patency of vein grafts are significantly compromised by Vein Graft Disease (VGD):
Endothelial Damage, Manifested Within Minutes as Pro-inflammatory, Pro-thrombogenic, and Hyper-proliferative Changes Within the Graft, Leads to VGD
As VGD progresses, vein grafts lose their ability to adapt to the post-grafting environment, leading to:
Thrombus formation • Intimal hyperplasia • Atherosclerosis
These may result in:
Graft stenosis • Occlusion • Loss of graft patency
DuraGraft® Treatment Improves Clinical Outcomes
*Manuscript being prepared for publication. Abstract was submitted to the EACTS.
1. Hess et al. Circulation. 2014 Oct; 130:1445-1451.
* Thatte et al., Ann Thorac Surg. 2003; 75:1145-1152
Printed with permission from the American Heart Association