The DuraGraft® CABG European registry is a prospective, multi-center, observational study to document clinical use of DuraGraft and associated outcomes of patients whose vascular grafts are treated with DuraGraft
JUPITER, Fla., Jan. 4, 2017 -- Somahlution, a global biotechnology company developing products to reduce the burden of ischemia reperfusion injury in tissue grafting, organ transplant and other surgical indications, today announced enrollment of the first subject in their DuraGraft® CABG European Registry.
JUPITER, FL – October 4, 2016 – Somahlution, a global biotechnology company leading the development of products to reduce the burden of ischemia reperfusion injury in tissue grafting, organ transplant and other surgical indications, today announced presentation of new data showing the company’s DuraGraft® vascular graft treatment significantly improves long-term outcomes in coronary artery bypass grafting (CABG) surgery. Results were presented today at the European Association for Cardio-Thoracic Surgery (EACTS) annual meeting in Barcelona, Spain.
Boston-based Dr. Miguel Haime will present oral abstract of clinical study results on the Company’s flagship product, DuraGraft®, at 2016 EACTS annual meeting in Barcelona.
Jupiter, FL (January 6, 2016) – Somahlution, a global biotechnology company focused on advancing the science of organ and surgical conduit transplantation, has announced that it has signed an agreement with Owens & Minor’s Movianto Group (O&M Movianto) to house and ship DuraGraft, globally.
Jupiter, FL (October 29, 2015) – Surgeons attended a satellite lunch symposium sponsored by Somahlution, Medistim and VGS to learn more about new technologies (including DuraGraft)...
Jupiter, FL (September 9, 2015) – Louis Perrault, MD, Ph.D., FRCSC, FACS, a leading cardiovascular and thoracic surgeon from the Montreal Heart Institute, recently presented the study design and progress for a multicenter, randomized, prospective study with DuraGraft.
Jupiter, FL–Somahlution announced today that its flagship product DuraGraft is available or will soon be available through key distributors in select EU countries including Germany, the UK, Spain, Austria, Switzerland, the Netherlands, Ireland, Italy and Luxembourg. DuraGraft has also recently received an Australian approval.
Jupiter, FL–Somahlution announced today that it has received European market (CE) approval for DuraGraft, the first-in-class Endothelial Damage Inhibitor (EDI) that uniquely protects vascular endothelium function and its associated architecture. DuraGraft, used as a vascular conduit solution, is a pivotal step in successful coronary artery bypass graft (CABG) and peripheral bypass surgeries.
The American Journal of Transplantation provides an essential resource for researchers and clinicians around the globe. The October issue of the journal features an article co-authored by Dr. Hemant Thatte -- a strategic advisor to Somahlution. The article showed compelling large animal data suggesting that a new preservation approach facilitates ambient temperature storage of donor hearts with superior function relative to hypothermic storage. Also visit the online library for additional content from this article.
In addition, the influential scientific journal Circulation has published a paper entitled, “Development and Evaluation of a Novel solution, Somah, for the Procurement and Preservation of Beating and Non-beating Donor Hearts for Transplantation”. Dr. Hemant Thatte, in conjunction with several co-authors, authored the publication.
Dr. Thatte is currently an Associate Professor of Surgery at Harvard Medical School (HMS) and Brigham and Women’s Hospital, and Director of Cardiothoracic Surgery Research at the VA Boston Healthcare System.
Thatte HS, Khuri SF. The coronary artery bypass conduit: I. Intraoperative endothelial injury and its implication on graft patency. Ann Thorac Surg. 2001 Dec;72(6):S2245-52; discussion S2267-70.
Biswas KS, Thatte HS, Najjar SF, Rhee JH, Birjiniuk V, Crittenden MD, Michel T, Khuri SF. Multi-photon microscopy in the evaluation of human saphenous vein. J Surg Res. 2001 Jan;95(1):37-43.
Thatte HS, Biswas KS, Najjar SF, Birjiniuk V, Crittenden MD, Michel T, Khuri SF. Multi-photon microscopic evaluation of saphenous vein endothelium and its preservation with a new solution, GALA. Ann Thorac Surg. 2003 Apr;75(4):1145-52; discussion 1152.
Thatte HS, Rhee JH, Zagarins SE, Treanor PR, Birjiniuk V, Crittenden MD, Khuri SF. Acidosis-induced apoptosis in human and porcine heart. Ann Thorac Surg. 2004 Apr;77(4):1376-83.
Rousou LJ, Taylor KB, Lu XG, Healey N, Crittenden MD, Khuri SF, Thatte HS. Saphenous vein conduits harvested by endoscopic technique exhibit structural and functional damage. Ann Thorac Surg. 2009 Jan;87(1):62-70.
Thatte HS, Rousou L, Hussaini BE, Lu XG, Treanor PR, Khuri SF. Development and evaluation of a novel solution, Somah, for the procurement and preservation of beating and nonbeating donor hearts for transplantation. Circulation. 2009 Oct 27;120(17):1704-13.
Hussaini BE, Lu XG, Wolfe JA, Thatte HS. Evaluation of endoscopic vein extraction on structural and functional viability of saphenous vein endothelium. J Cardiothorac Surg. 2011 Jun 10;6:82.
Hussaini BE, Treanor PR, Healey NA, Lu XG, Khuri SF, Thatte HS. Multifactorial comparison of modified and conventional perfusion strategies in a porcine model of cardiopulmonary bypass. J Surg Res. 2011 Jun 1;168(1):e7-15.
Lowalekar SK, Lu XG, Thatte HS. Further evaluation of Somah: long-term preservation, temperature effect, and prevention of ischemia-reperfusion injury in rat hearts harvested after cardiocirculatory death. Transplant Proc. 2013 Nov;45(9):3192-7.
Lowalekar SK, Cao H, Lu XG, Treanor PR, Thatte HS. Subnormothermic Preservation in Somah: A Novel Approach for Enhanced Functional Resuscitation of Donor Hearts for Transplant. Am J Transplant. 2014 Oct;14(10):2253-62. doi: 10.1111/ajt.12846. Epub 2014 Aug 25.
Lowalekar SK, Cao H, Lu XG, Treanor PR, Thatte HS. Sub-normothermic preservation of donor hearts for transplantation using a novel solution, Somah: A comparative pre-clinical study. J Heart Lung Transplant. 2014 Sep;33(9):963-70. doi: 10.1016/j.healun.2014.05.006. Epub 2014 Jun 9.
Lowalekar SK, Treanor PR, Thatte HS. Cardioplegia at subnormothermia facilitates rapid functional resuscitation of hearts preserved in SOMAH for transplants. J Cardiothorac Surg. 2014 Sep 20;9(1):155.